This article gives an overview of the study conducted to investigate whether acid-suppression medication increases the risk of bacterial gastroenteritis. This study was performed in the community and hospital settings. Study Background Bacterial gastroenteritis is one of the major global challenge associated with increased morbidity, mortality. Clostridium difficile is one of the most prevalent organisms causing infections. C.

difficile is more common in the hospital settings than in the community. Some of the underlying factors for C.difficile infection include old age, antibiotic use, hospitalization, comorbid illness, and gastrointestinal procedures. Other infections like Campylobacter, Salmonella, Shigella and Escherichia coli O157 account majority of the infections in the community settings. Generally, proton-pump inhibitors (PPIs), and histamine-2 receptor antagonists (H2RAs) are…