Azathioprine is a thiopurine immunosuppressant drug that occupies an important place in the management of many autoimmune and inflammatory skin diseases. Although azathioprine has been widely prescribed since the 1960s, there continue to be developments in the understanding of drug action, pharmacogenetics and toxicology. The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the safe and effective use of azathioprine . The guideline is presented as a detailed review with highlighted recommendations for practical use in the clinic, in addition to updated patient information. Use of Azathioprine: 1.
Indication s Azathioprine is licensed for use in Systematic lupus erythematosus. As a second-line agent in patients with dermatomyositis. Polymyositis. There is evidence to support the use of azathioprine outside its product license for the…
