Acute interstitial nephritis forms an important cause of acute renal failure that results due to immune-mediated tubulointerstitial injury, initiated by medications, infection, and other causes. It is prevalent in 15 % of patients hospitalized for acute renal failure. This article summarizes the pathogenesis and diagnostic approaches for intestinal nephritis. Acute interstitial nephritis is a renal lesion resulting in a decline in renal function and is characterized by an inflammatory infiltrate in the kidney interstitium.
It is most often induced by drug therapy. Although the term acute interstitial nephritis is more commonly used, acute tubulointerstitial nephritis more accurately describes this disease entity, since the renal tubules, as well as the interstitium, are involved. Aetiology Drug-induced intestinal nephritis Drugs are more frequently recognized as aetiologic agents in…
