A few months ago a post was placed on this platform requesting advice for hormonal management of a 48-year-old premenopausal woman in a remote Caribbean Island, whose receptor status was unavailable. The response was moderate and almost all responders advised not to commence on adjuvant hormone therapy without hormone receptor status. Concerns were about: side effects ineffective therapy for receptor negative cases Unnecessary cost.
While considering adjuvant Hormone therapy for Breast Cancer, an educated insight must be the driving force to make the correct decision and appropriate choice. Following facts should certainly influe nce us in making the correct decision: It has been demonstrated over and over again that the beneficial effect of Tamoxifen, far outweighs the side effects of these agents, not only in controlling recurrence, but also prevention of cancer in the contralateral…