Excess aldosterone, especially from primary aldosteronism , significantly increases the risk of cardiovascular and end-organ damage , often beyond what is seen in essential hypertension. Recent studies show that renin-independent aldosteronism can present subclinically at any age and drive early cardiac remodelling, even in young adults, regardless of blood pressure. Importantly, individuals with primary aldosteronism have higher cardiovascular morbidity and mortality compared to those with blood-pressure-matched hypertension. Early diagnosis and intervention with mineralocorticoid receptor antagonists can substantially reduce these risks. To read more click here .
##Reference## Ananda RA, Mori TA, Yang J. Aldosterone and cardiovascular risk across the lifespan. Metabolites. 2025;15(8):553.## In your experience, what is the most effective approach for managing subclinical primary…
