After the authorization of Covishield and Covaxin, Sputnik V has made its way to India. Although Indians are yet to receive the vaccine, it is important to know everything about the vaccine before receiving it. We’ve summarized the crucial and clinically relevant information about the Sputnik V vaccine. The vaccine Sputnik V is the world’s first human-adenoviral vector-based vaccine . It confers 97.6% efficacy and is approved in more than 65 countries.
The vaccine is administered in two doses (0.5 ml each) and stored at +2 to +8°C. The first component of Sputnik V is named “Sputnik Light” which is a recombinant human adenovirus serotype number 26 (rAd26). The Sputnik Light is shown to initiate the development of antigen-specific IgG antibodies in 96.6% of recipients. The antibody formation commences on the 28 th -day post-vaccination while the cellular response against the S protein…