Alport Syndrome is an inherited disease of the kidney that can also affect the inner ear (cochlea) and eye. It is caused by genetic mutations that affect the type IV collagen family of proteins. This article briefly covers symptoms, diagnosis, and treatment of the Alport syndrome. Alport syndrome is characterised by renal, cochlear and ocular involvement.
If not treated on time this renal disease progresses from microscopic hematuria to proteinuria, progressive renal insufficiency, and end-stage renal disorders, in all males with X-linked AS (XLAS) and in all males and females with autosomal recessive AS. Symptoms: Progressive sensorineural hearing loss is usually present by late childhood Ocular findings include anterior lenticonus Maculopathy Corneal Endothelial vesicles Recurrent corneal erosions Diagnosis: Renal Hematuria. In XLAS, 100% of affected males and more than 90% of…
