Klinefelter syndrome (KS) (47XXY) can be broadly defined as a chromosomal condition in boys and men. The syndrome affects the physical and intellectual development of the patient and is usually characterized by infertility. However, an interesting case was observed when a patient with KS was confirmed for paternity by human leukocyte antigen (HLA)-typing. The case The patient was first brought to the hospital at 12 with a complaint of bilateral mobile testes.
A routine buccal smear analysis revealed a positive 29% sex chromatin and the 47 XXY karyotype in 100% of the peripheral leukocytes cultured, confirming the diagnosis of KS. Spontaneous onset of puberty An unprompted onset of adolescence was detected at the age of 13 years and 3 months, when the bone age was found to be 10 years and 6 months. Afterward, there was a gradual upsurge in testicular volume, from 1.5 to 10 ml…
