Case presentation A 37-year-old male presented to the primary care clinic with a six-week history of a tender mass in the right breast. Over the past five months, he had experienced a 40-pound weight loss along with a decreased appetite. He denied having a fever or night sweats and reported no use of hormonal or nutritional supplements.

There was no known family history of breast cancer or endocrine disorders. Physical examination Vital Signs: Normal The patient appears thin with a body mass index (BMI) of 21.6 Breast examination: One-centimeter-by-one-centimeter tender mass without nipple discharge Thyroid gland: Nonpalpable No evidence of lymphadenopathy Laboratory findings TSH : 0.01 mIU/L (Reference range: 0.40–4.5 mIU/L) Free T4 : 3.3 ng/dL (Reference range: 0.93–1.7 ng/dL) Total T3 : 335 ng/dL (Reference range: 80–200 ng/dL) Thyroid-stimulating immunoglobulin level : >500 (Normal…