Angelman syndrome is a genetic disorder that causes developmental delay and neurological problems. Angelman syndrome (AS) is seen in one in 12,000–20,000 of the population. This article presents an overview of the Angelman syndrome. Angelman syndrome is a complex genetic disorder that primarily affects the nervous system. Characteristic characteristics of Angelman syndrome include delayed development, intellectual disability, severe speech impairment, and problems with movement and balance (ataxia).
Most affected children begin to develop seizures between 2 and 3 years of age and possess a small head size (microcephaly). Delayed development becomes noticeable by the age of 6 to 12 months, and other common signs and symptoms usually appear in early childhood. Genetic mechanism Deletion: Deletion contributes for Angelman syndrome in 65-75% of the families. Many of the characteristic…
