Anus is a part of  human  gastrointestinal / digestive  system. A nature  creation like a guard at the end of humans gastrointestinal tract guided by external & internal sphincter at its lower edge.

Comparison may be done with crycoesopharyngeal sphincter at esophagus or the labialis at lips of mouth. Anoitis/anal inflammation could be due to: Anal Trauma Direct physical trauma Anal sexual perversions A route for smuggling   Anal  instrumentation Anal infections includes : Bacterial/ viral/ fungal/ protozoal/ helmenthic/ sexual et fissures Inflammatory secondary to inflammatory   bowel disease  ( ulcerative  colitis / Crohn's disease / Tuberculosis   & other geanulomatous diseases Anal fissures PerI anal abscess / peranal  glandular   infections  /abscess   Malignancies / carcinomas  of anal canal    primarily /could be secondary fissures Secondary to normal physiological illness - A…