Rabies is one of the most painful and dreadful of all communicable diseases in which the sick person is tormented at the same time with thirst and fear of water (hydrophobia) with an obvious consequence of death. Fortunately, development of rabies can be prevented to a large extent if animal bites are managed appropriately and in time. We have already discussed the guideline related to decision to treat post rabid dog bite .
Two major steps in PEP are: Wound management (Wil be discussed in next article) Active immunization Active immunization is achieved by administration of safe and potent cell culture vaccines (CCVs) or purified duck embryo vaccine (PDEV). Currently available CCVs could be administered by IM regimen and CCVs approved for ID use shall be administered by ID regimen. Anti-rabies vaccines are produced as one single intramuscular dose with potency of > 2.5IU per IM dose…
