Ischemic Stroke, a circulatory disease, practice, belong to cardioembolic or atheroembolic and cryptogenic category. The timing of starting anticoagulation was early in practice, later become a late practice in view of heamorhagic conversion with Vit K antagonist oral anticoagulants. Chance of recurrence of stroke after AF is between 2-4% in the first 2 weeks.
With introduction of newer direct oral anticoagulants (DOAC) like dabigatran, apixaban, rivaroxaban and edoxaban in various new studies like RE-LY, ARISTOTLE and ROCKET -AF Trials starting early DOAC is better to prevent recurrence of events because they observe chance of recurrence of ischemic events is 6 times higher than chance of heamorhage. So early start of DOAC is recommended to prevent recurrence since the chance of heamorhage is less. Kindly share your views for DOAC in small and large cardio embolic strokes, you prefer…
