THE PATIENT CASE: A 50-year-old man with a history of bladder cancer presents with abnormal findings on urine cytology. Computed tomographic urography is planned for further evaluation and minimizing the risk of contrast-induced nephropathy. Medications Enteric-coated aspirin, 81 mg/d Lisinopril, 10 mg/d Laboratory Results Sodium, 145 mEq/L (to convert to mmol/L, multiply by 1) Potassium, 3.8 mmol/L Creatinine, 1.7 mg/dL (to convert to μmol/L, multiply by 88.4).
Estimated glomerular filtration rate (GFR), 46 mL/min per 1.73 m2 (reference range, >90 mL/min per 1.73 m2) DISCUSSION: Contrast-induced nephropathy, a well-recognized complication of procedures and imaging studies requiring the use of iodinated contrast medium, is linked to increased morbidity. Although a variety of definitions exist, it is generally defined as an increase in serum creatinine level greater than or equal to 0.5…
