A contemporary analysis of preterm infants with patent ductus arteriosus showed that using ductal size alone as an enrollment criterion would classify nearly half of screened infants as eligible for early PDA treatment trials, regardless of hemodynamic impact. Applying a broader physiology‑based echocardiographic framework—integrating shunt direction, ventricular loading, and systemic perfusion—more accurately identified high‑risk PDA phenotypes. The authors argue that future trials and bedside decisions should prioritize hemodynamic adjudication over diameter thresholds to avoid overtreatment. To read more Click Here ##Reference## Bischoff AR, et al. Beyond diameter: redefining echocardiography criteria in trials of early PDA therapy.
J Perinatol. 2025;45(Online ahead of print):pp–pp. doi:10.1038/s41372-025-02523-7.## In your experience, which factor most strongly guides your…
