Though majority of patients with asthma respond to conventional therapy, treatment choices are limited for those with severe persistent disease that require high dose steroids. Biological therapeutic solutions aim at interrupting the pathogenic inflammatory processes. Controlling and treating asthma has been an age old challenge for clinicians due to heterogeneous pathophysiology and the variable response to treatment. A complex interplay of environmental physiological and genetic factors dictates the pathological processes.
Therapeutic regimens aim at acute symptom relief and long term control of airway inflammation. Majority of patients respond to a combination of glucocorticoids, beta-agonists and leukotriene receptor antagonists. Reducing the exposure to trigger factors, such as environmental allergens is also an integral part of asthma management. These solutions require lifetime…
