Using an advanced approach of immunoproteomics, to broadly sift through the entire repertoire of immune system proteins in the blood and identify early bell weathers of Crohn's disease, a group of researchers from the US identified new biomarkers that can be used for diagnosis of the diseases. Current challenges The cause of Crohn's disease remains unknown with no simple medical explanation or cure. But in the course of the disease, the body's own immune system somehow triggers an attack on the gut. Crohn's is often associated with chronic, debilitating stomach pain, diarrhea, and other symptoms that may come and go.

One in five people get hospitalized each year, and surgery may eventually be required for the most severely afflicted. Inflammation is often a sign that the immune system has been triggered. Crohn's diagnosis can be very difficult, and involves either expensive medical…