Along with the rising incidence of diabetes worldwide, the clinical burden of diabetic foot ulcer (DFU) is also likely to increase, especially in the absence of an improved and effective treatment strategy. To address this gap, researchers investigated the effectiveness of a new and innovative DFU treatment strategy. They fabricated levofloxacin-loaded polycaprolactone scaffolds with different designs using 3D bioprinting technology. The scaffold showed antibacterial and wound-healing properties in vitro.
Design details The scaffold has two molecular layers to promote wound healing. The ‘frame’ of the scaffold holds an antibiotic and a collagen/sodium alginate-based component containing growth factors to encourage cell growth. Benefits Greater freedom of mobility than with total contact casts Can be modified based on the wound size Flexibility: Offers minimal resistance to normal…
