Beta amyloid plaques formation and associated inflammation is the hallmark of Alzheimer’s disease (AD). Several pharmacological ingredients went under clinical trials that showed prevention in plaque formation. This article outlines the hypothesis behind the use of active marijuana compound THC in AD, the mode of action of THC and the study that showed the positive effect of THC in AD prevention. Neurodegenerative disorder Alzheimer’s disease (AD) is characterized by dementia and complex cognitive decline.
Pathologically, AD results from over time accumulation of beta amyloid plaques and neurofibrillary tangles. The amyloid plaques occupy the space between the neurons as dense cluster. The neurofibrillary tangles are thick insoluble clumps resulted from the defect in tau proteins. Basis of the hypothesis No certain reason behind the accumulations of the plaques and the tangles in the…
