This randomized clinical trial investigated whether subcutaneous nitroglycerin could reduce the risk of radial artery occlusion ( RAO) in children under 3 years old undergoing arterial catheterization. A total of 132 participants were randomized to receive either subcutaneous nitroglycerin or saline before catheter removal. The results demonstrated a significant reduction in RAO incidence in the nitroglycerin group ( 25.4% ) compared with the control group ( 73.8% ). Additionally, higher peak blood flow velocity and perfusion index were observed in the intervention group, without any notable adverse effects such as hypotension.
These findings highlight subcutaneous nitroglycerin as a safe and effective strategy to prevent RAO in pediatric patients, offering potential improvements in vascular care for young children. ##Reference## Zhang H, Li X, Chen Q, et al. Subcutaneous nitroglycerin…