Psychological stress is a well-established risk factor for early-onset ischemic stroke . However, its impact on cryptogenic ischemic stroke (CIS) remains largely undocumented. To address this gap, a study has examined the relationship between varying levels of stress and CIS in 426 patients (aged 18-49 years) with CIS and 426 controls. The study found that a higher proportion of CIS patients experienced at least moderate stress compared to controls (46.2% vs. 33.3%). Analysis using the Perceived Stress Scale demonstrated a significant and independent association between moderate stress and CIS (adjusted odds ratio [OR] – 1.47).
Notably, moderate (78% vs. 6%) and higher stress levels (6% vs. 2%) were associated with CIS in women, but not in men. These findings highlight a strong association between stress and an increased risk of early-onset CIS, particularly among women. Did you find…
