A 30 year old woman was presented with c/o chronic thirst, polydipsia, and polyuria. PMH: The symptoms have been present for many years and seem to increase during her pregnancies. Several years before, she had a sugar and dehydration test done, after which the physician told her not to worry as she simply “drank too much”. She is otherwise healthy and takes no drugs. She was adopted at an early age and knows nothing of her biological family. Physical Examination: CBC and chemistry profiles are WNL.
Her 24-hr urine volume and osmolarity are 6.5 litres and 125 mmol/kg respectively. A fluid deprivation test increases her urine osmolarity and plasma sodium to maxima of 465 mmol/kg and 141 meq/L, respectively, after four hours. It also increases her thirst. What should be the approach for the management of this patient? *This case is from the Docplexus Editorial Team and is meant for…
