An initial change in the brain triggered by environmental events followed by a cascade of knock-out effects triggers the development of neurological and psychiatric diseases. The lack of diagnostic capabilities is attributed to the lack of substantial understanding of the cascades involved. As a result, most diseases are diagnosed and grouped in to syndrome in terms of cognitive and behavioral symptoms as opposed to objective biological markers. This creates a severe risk of misdiagnosis, to the point that autopsies studies of almost 20% Alzimer’s patients fall into this category.
Further, this also results in delayed identification and diagnosis of these diseases beyond the point of reversibility. Meanwhile, pharmaceutical companies are forced to invest in drug candidates without fully understanding their mechanism of action or potential side effects. Currently there are no drugs known…
