Objective: to compare the efficacy of these two when used as adjuvants to hyperbaric bupivacaine for SA for lower limb surgeries. Methods:  This randomized control trial was conducted at the Department of Anesthesia Ghulam Muhammad Mahar Medical College/Hospital, Sukkur, Pakistan. A total of 36 patients were randomly assigned to receive unilateral spinal anesthesia with bupivacaine 2.5 ml. Group F (n = 18) received 25.

g fentanyl and Group D received 10? g DEX added to the spinal bupivacaine. Time to first analgesic request was the primary outcome, while sensory and motor block characteristics, nalbuphine consumption as rescue analgesia, pain scores, side effects, and sedation levels were the secondary outcomes. Results:  Patients receiving dexmedetomidine as an adjuvant to hyperbaric bupivacaine for spinal anesthesia for lower limb surgeries had a significantly longer time to rescue…