An early appropriate treatment showed no benefit on survival rates and other outcomes reported a new study published in Clinical Infectious Diseases. The study demonstrated that in patients with complicated urinary tract infections (cUTIs) appropriate empirical antibiotic treatment displayed no benefit in treatment failure rates nor in 30-day mortality. The study comprised 981 patients with cUTI. Furthermore, study suggests that management variables, such as inappropriate empirical antibiotic treatment or delay in antibiotics starting were not associated with treatment failure or 30-day mortality.
Similarly, more patients with pyelonephritis were given appropriate empirical antibiotic therapy when compared with other CUTI [110/171 (64.3%) vs. 116/270 (43%), p<0.005], but it demonstrated no advantages in treatment failure. Source: Noa Eliakim-Raz, Tanya Babitch, Evelyn Shaw, Ibironke…
