Cutaneous manifestations appear in approximately 25% of sarcoidosis patients, with skin lesions often associated with pulmonary and osseous involvement. However, most frequently, these lesions occur in association with other systemic abnormalities. A stepwise approach to patient care is appropriate, hence, the current article reviews the conventional therapies used for cutaneous sarcoidosis based on evidence-based data.
PATHOGENESIS Sarcoidosis is a multisystem disorder characterized by non-caseating granulomata that primarily affect the lungs and lymphatic system, but may further involve the skin, eyes, liver, spleen, nervous system, muscles, bones and other visceral organs. The granulomas of sarcoidosis represent the accumulation of lymphocytes and mononuclear phagocytes, with secondary derangement of normal tissue or organ anatomy and function. Although some sarcoidosis patients…
