Modern cities with its urban slums/villages face the emergence of new infections in the host populations. This includes HIV, Dengue, Zika, KFD (endemic tick-borne), Malaria, Cholera, and newer strains of influenza. Flooding in the cities after heavy rains does result in sewage overflow forming pools of stagnant water and widespread water contamination (cholera and diarrhea). Ecological interactions involve population movement from rural areas to cities and the spread of a once-localized infection.

Rise in insect vector population is consequent to climate change , overcrowding, and poor sanitation. The virus, bacteria, and phages (virus that infect bacteria ) with bio-active compounds from saliva inoculated by vector into the host tissue interact together to overcome the host antiviral defense. Travel to distant destinations allows the infected hosts to carry the diseases to other towns…