A 77-year-old man with a past medical history significant for dementia, hyperlipidemia, coronary artery disease (CAD), s/p coronary artery bypass graft (CABG), and aortic valve replacement (AVR) was referred for agitation. According to the patient’s wife, he started having memory problems four years back, which worsened significantly after his CABG and AVR two years ago. The patient was observed to have functional deficits in the instrumental activities of daily living (IADLs) such as handling finances, driving, cooking, and shopping.

The patient was noted to be easily agitated and irritable for some time and was referred to a memory clinic for exhibiting verbal and physical aggression towards his wife as well as others. The patient was recently seen by his primary care physician for this issue, and all of his laboratory exams were normal, and subsequent MRI of the brain was also…