A middle-aged cargo terminal worker with a history of long-standing alcohol dependence that was further complicated by parenchymal liver disease and marital tension was prescribed disulfiram for relapse prevention after completing a detoxification program at an in-patient psychiatric hospital. He received disulfiram 400 mg every Monday and Wednesday and 600 mg every Friday under the direct supervision of a nurse at the outpatient clinic. After this intervention, he was mentally stable and resumed work for two weeks.
But one day after taking his regular dose of disulfiram without any alcohol use, he developed acute mental confusion. Upon admission to the general hospital following parameters were noted: Mental examinations: Irrelevant speech, irritable mood, auditory hallucination, disoriented to time, place, and person Physical examination: Unremarkable for alcohol withdrawal sign,…
