A 31-year-old woman presented to the emergency department following minor trauma to her upper lip. She was injured while bending down to pick up a bag and struck her right upper lip against a metal pole. There was an absence of external trauma, ecchymosis or laceration. Shortly following the trauma, she noticed that her lip was markedly swollen.

Subsequently, the swelling increased and extended to her right cheek and submental region despite management with ice and pressure. She denied any recent insect bites, illicit drug use, food or drug allergies, herbal medications, and consumption of food precipitants. Medical history Rheumatoid arthritis managed with methotrexate and a reducing course of steroids Hypertension treated with captopril (Angiotensin-converting enzyme inhibitor (ACEi)) Examination Temperature : 97.4 ◦ F Heart rate : 70 beats/min Blood pressure : 115/64 mmHg SPO 2 : 98%…