Non-invasive detection strategies for diagnosing urothelial bladder cancer (UBC) such as liquid biopsies will allow the identification of highly prognostic (or predictive) biomarkers. This could help in guiding patient management, especially for high-risk patients. This article gives an overview about potentially significant future utilities of this technique and current challenges. A liquid biopsy or fluid biopsy is the sampling and analysis of non-solid biological tissue, primarily blood. This non-invasive technique is mainly used as a diagnostic and monitoring tool for diseases such as cancer.

As it is non-invasive, it can also be done more frequently which can help better monitoring of tumors and mutations over time. It may also be used to validate the efficiency of a cancer treatment. For bladder cancer, this technique relies on analysis of biomarkers present in the urine. Liquid…