History A 31-year-old woman has presented to the emergency department with significant bruising on her arms and legs that have been getting worse. She first noticed them five days ago when they started off as small bruises. She intended to visit her GP but noticed they were now larger and more widespread. She has had no fevers, arthralgia or recent viral infections, and she is not taking any medications. Examination This woman looks systemically well. There is a marked petechial rash over her legs with large bruising on the arms and legs.

A cardiovascular and respiratory exam is normal. On abdominal examination, there is no hepatosplenomegaly and there is no lymphadenopathy. Observations: temperature 36.8°C, heart rate 78/min, blood pressure 135/67 mmHg, respiratory rate 18/min, SaO2 98 percent on air. What is the most likely diagnosis? How should this patient be managed? *This case is…