Drug-induced acute pancreatitis (DIP) occurs in ~ 2% of the cases. But the problem is often underreported due to the difficulty appreciating a drug as its cause. Although the severity of majority of drug-induced acute pancreatitis is mild to moderate, fatal consequences may occur.
This article deals with the mechanism, a step-by-step diagnostic approach and ultimate management of drug-induced acute pancreatitis. The Mortality of Acute Pancreatitis (AP) varies significantly between mild and severe disease (mild < 5% vs severe 20–25%), and early assessment of the severity is essential. There are many causative factors for AP, including gallstones, alcohol abuse, endoscopic retrograde cholangiopancreatography and manometry, surgical procedures near the pancreas, infection, chronic hypercalcemia, and hyperlipidemia, However, it takes critical clinical judgment to detect whether drugs are…
