Medications such as thiazide diuretics, calcium channel blockers, renin-angiotensin system (RAS) inhibitors, statins, antidepressants, contraceptives, antipsychotic drugs, steroids, and growth hormone therapies may induce hyperglycemia, which can eventually progress to diabetes mellitus. The pathophysiology behind this is attributed to an alteration in insulin secretion and sensitivity, direct cytotoxic effects on pancreatic beta cells, or an increase in glucose production. These effects can either be managed by dose alteration, cessation of the drug, or by administration of alternate medicines associated with a lower risk of hyperglycemia.
The key point here remains to be vigilant over such known adverse effects and make an early intervention to prevent the complications of diabetes. For detailed insights on “Drug-induced Diabetes,” join Dr. Manish Agarwal , an expert diabetologist,…
