Many studies have reported drug-induced gynecomastia in patients. This article reviews the drugs that have been implicated by the scientific literature for inducing gynecomastia. The genesis of gynecomastia, the clinical presentation or symptoms, and the hormonal level vary in every case, and hence it is recommended to perform a drug surveillance to reduce such incidents. Gynecomastia is defined as the presence of palpable, subareolar breast tissue with a diameter of 2 cm or greater.
Generally, it is asymptomatic, however highly prevalent in obese and aging population. Although the etiology is uncertain, many reports and studies have reported numerous medications being associated with gynecomastia. This article reviews different drugs reported in the literature responsible for the clinical manifestation of the breast enlargement. Men with gynecomastia mainly complain or manifest…
