Pemphigus is an umbrella term used to describe a rare cluster of bullous autoimmune diseases that affect the skin and mucosal membranes. The main symptomatic presentation of pemphigus is the widespread flaccid blisters and erosions erupting on the oral mucosa and skin. Drug-induced pemphigus is mainly caused by a combination of aberrant stimulation of host B cells producing intracellular IgG antibodies and biochemical reactions in the body. Of all etiological factors, drug-induced pemphigus is most prevalent.
The incidence of pemphigus is rare and has been estimated to affect one out of every 100,000 people. Hence, physicians need to differentiate this condition from other drug-related allergic diseases. Take this short quiz to refresh your knowledge on Drug-Induced Pemphigus. Source: Journal Of European Academy Of Dermatology And Venerology
