Highlights Dual-polymer HA + HP-Guar provides double-action hydration to the surface of the eyeball. HA/HP-Guar demonstrated protection against desiccation in in vitro model of corneal epithelium HA/HP-Guar reduced hydrodynamic surface friction compared to HA alone in vitro testing. Why This Dual Polymer Matters Dry eye disease (DED) involves desiccation and damage of ocular surface tissues and disrupted epithelial cell barrier function.
Lubrication, replenishing moisture and decreasing friction is a primary approach to DED management. Many single component artificial tears replace only the aqueous components of the tear film and require frequent administration to maintain efficacy, thus longer-acting formulations are needed that have increased hydration and lubrication effects. The dual-polymer HA/HP-Guar formulation demonstrated hydration and lubricity effects in in-vitro models of…
