Invasive mould infections (IMIs), such as invasive aspergillosis or mucormycosis, are a major cause of death in patients with hematological cancer and in patients receiving long-term immunosuppressive therapy. Early diagnosis and prompt initiation of antifungal therapy are crucial steps in the management of patients with IMI. The diagnosis of IMI remains a major challenge, with an increased spectrum of fungal pathogens and a diversity of clinical and radiological presentations within the expanding spectrum of immunocompromised hosts.
Imaging, microbiological tools, and histopathology are crucial for the diagnostic work-up of IMI. Imaging technologies Clinical signs of IMI are often absent or non-specific at early stages of the disease but suggestive radiological findings are frequently the first diagnostic modalities to identify and aid to initiate antifungal therapy. High-resolution CT…
