A 47-year-old woman was diagnosed with polycystic kidney disease when she was 25. For many years, she had no symptoms, but in her early 40s, blood tests showed decreased kidney function. Her nephrologist said she would need a transplant within a few years. Eleven family members and friends offered to donate a kidney. The first three candidates were incompatible, but her step-sister was a good match. She had elevated antibody levels.

The transplant surgery went well, but several days after discharge, she demonstrated signs of B-cell rejection. The patient was readmitted to the medical center. How will you manage elevated antibody levels and B-cell rejection in this patient? ##Disclaimer## The content provided on Docplexus is intended for educational purposes only. While we strive to ensure its accuracy, we make no warranties, explicit or implied, about the suitability, reliability, or…