Exposure to exogenous chemicals can impact endocrine function at multiple sites and through numerous specific modes of action, which may have far-reaching impacts on human health and development. Widespread human exposure to numerous known or suspected endocrine disrupting chemicals (EDCs) has been documented worldwide, as have trends for increased rates of endocrine-related diseases and disorders among children.
Several common EDCs (with a specific focus on persistent organic pollutants, phthalates, bisphenol A, and contemporary use pesticides, which only represents a small number of all known or suspected EDCs ENDOCRINE DISRUPTING CHEMICALS Persistent organic pollutants : are lipophilic chemicals with long half-lives that bioaccumulate up the food chain, and include polychlorinated biphenyls (PCBs), organochlorine pesticides (such as DDT, chlordane, and hexachlorobenzene),…
