An endometrium is receptive when it is ready for the embryo implantation. This occurs around days 19-21 in each menstrual cycle of a fertile woman. This period of receptivity is what we call the window of implantation. The lack of synchronization between the embryo ready to be implanted and endometrial receptivity is one of the causes of recurrent implantation failure. This is why it is imperative to assess the endometrium in order to determine the optimal day for embryo transfer.
The E ndometrial Receptivity Array (ERA) test requires an endometrial biopsy that should be carried out on day LH+7 (natural cycle) or day P+5 (HRT cycle). This biopsy is quickly and easily taken by a gynecologist in their consultation room. After being sent away, the sequencing expression of 238 genes involved in the endometrial receptivity is analyzed. An in-house designed computational predictor analyses…