Causes of brain damage include hypoxia, ischaemic, seizures, hypoglycaemia, and possibly hyperglycaemia. These disorders disrupt the normal integration of cerebral blood flow (CBF), metabolism, and neurotransmitter function to produce cerebral damage. Although hypoxia, seizures, hypoglycaemia and hyperglycaemia can occur during anaesthesia, ISCHAEMIA is the most common cause of neurological complications after surgery. Both Focal & Global ischaemia can occur during surgery, particularly Cardiac surgery.
FOCAL ISCHAEMIA: is impaired perfusion of a region of the brain that produces localised sequele and may be caused by 1. EMBOLISM::- Most neurological sequelae occurring after cardiac surgery are Focal, and emboli have been implicated as the most The common source of these Focal events. Sources of emboli during cardiac surgery include Air Atheromatous plaque Microemboli Left ventricular…