A recent study from the UK has confirmed that mild autonomous cortisol secretion (MACS) increases the risk of hypertension, type 2 diabetes mellitus in individuals with benign adrenal tumors. Women were found to be more affected than men. Adrenal incidentaloma has become a frequent clinical problem. These benign tumors may secrete cortisol profusely, leading to a condition known as mild autonomous cortisol secretion (MACS) 1 .
Several evidences indicate implications of MACS in impairment of glucose metabolism, hypertension, and other metabolic disorders 2 . Recently, a cross-sectional, multicenter study with a large population confirmed the significant association of MACS with higher prevalence and severity of metabolic diseases. Study details Key findings MACS-2 and CS cohorts showed a higher prevalence of hypertension, use of three or more antihypertensive agents, and were twice more…
