Dawn of new therapies in oncology improved survival of patients with challenging neoplasm. But, these treatments often associated with toxicity. A physician must be intended to learn these treatments and their side effects to save lives of many patients. Understanding the genetics behind melanoma can help to better learn these practices and develop new therapeutic targets. Thus, the present editorial is a synopsis of a recent article appeared in a reputed dermatology journal.

A DNA damage in skin cells through ultraviolet radiations can cause a serious form of skin cancer. It is well-known fact that melanoma pathology involves many gene pathways, and to identify driving mutations is not an easy task. The malignant tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis of the skin. The majority of melanomas resemble like moles or may originate from…