Case of a Female with Galactorrhea, What's Your Diagnosis?

  . Case presentation A 27-year-old female presented with headaches, hot flashes, galactorrhea, and eight-week delayed periods. She did not complain of any vision or weight fluctuations problems, quit smoking five years ago, and was an occasional drinker. She had a medical history of asthma and irritable bowel syndrome. She was noted to have galactorrhoea on expression, and physical examinations revealed a 10 cm supra-pubic mass.

Investigations Prolactin: 24, 642 mIU/l (normal range 50–400 mIU/l) TSH: 1.8 mIU/l (0.30–5.00) Thyroxine: 12 pmol/l (9–25 pmol/l) Normal cortisol response to short synacthen test MRI images of the pituitary were normal. Computed CT of the abdomen has been provided (Cover image A). She was treated with right salpingo-oophorectomy with para-aortic node clearance, following which her prolactin levels dropped to normal. Immunohistochemistry was performed, and…