In asthma, a long-acting beta agonist can be added to treatment if an inhaled corticosteroid is insufficient to control the patient's symptoms. Inhaled corticosteroids can also be added to long-acting beta agonists to try and reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD). What are the benefit of combination therapy over monotherapy of either class of the molecule? Fluticasone propionate is already available in combination with salmeterol for both conditions.
The combination of fluticasone furoate with vilanterol trifenatate is another option for delivering a corticosteroid and a long-acting beta agonist by inhalation. These combinations have anti-inflammatory effects and relax bronchial smooth muscle. The present article discuss some comparative aspect of this combination with monotherapy and few other available combinations. Fluticasone…
