Fluticasone is majorly available as an intranasal glucocorticoid in treating rhinitis and asthmatic conditions. There are two distinct formulations available depending upon steroidal backbone (fluticasone) and the ester substituent (furoate/propionate), Fluticasone Furoate (FF) and Fluticasone Propionate (FP). FF and FP are completely different drugs with FF showing distinct and superior properties. This discussion takes you through the different formulations of fluticasone with the use, dosage and adverse effects.
Mostly used for allergic rhinitis and asthma prophylaxis but also have cutaneous application in some cases. Indication and dosage Indication: Allergic rhinitis Form: Nasal Dosage: Adult: As fluticasone propionate spray: 100 mcg into each nostril once daily, increased to bid as necessary. As fluticasone furoate spray: 55 mcg into each nostril once daily, may reduce to 27.5…
