Fracture-related infections (FRIs) are one of the most challenging complications in musculoskeletal trauma surgery . Management of FRI’s lack guidelines on diagnosis and treatment compared to periprosthetic joint infections (PJIs) . The key aspects of these implant-associated infections differ in approach. In PJIs, removal of fracture fixation devices after osseous healing occurs without functional loss. While in patients with FRI, antibiotic suppression may be a curative option until bone consolidation.
A recent study revealed that FRI results in amputation in 3-5% of cases. Therefore, finding standard management of FRI is essential for surgeons, clinical microbiologists, and infectious diseases specialists. Pathogenesis of FRIs Efficient management of FRI calls for a combination of surgical and antimicrobial treatment. Hematogenous infections are negligible, while polymicrobial…
