Anderson-Fabry disease is caused by a mutation in the a-galactosidase A enzyme (GLA) gene that leads to the deficiency of the enzyme. The a-galactosidase A deficiency causes deposition of globotriaosylceramide, a glycosphingolipid, in lysosomes of the cells in all body parts, including eyes, kidneys, nervous system, heart, and skin. It is an X-linked disease that predominantly affects males with less than 1% a-galactosidase A enzyme activity. The symptoms of Fabry disease include pain in extremities, lenticular and corneal opacities, abnormal sweating, proteinuria, and vascular cutaneous lesions.
Do you know which of the following condition could result from globotriaosylceramide deposition in the heart? Hyperplasia Cardiomegaly Left ventricular hypertrophy Myxoma *This question is from the Editorial team of Docplexus and is meant for educational purposes only. (The correct answer is…
