Gut microbes under normal conditions have a symbiotic relationship with the host. Alterations in the structure and function of the gut microbes play a key role in the pathogenesis of numerous diseases including cardiometabolic complications. This article briefly describes the role of gut microbiota in the regulation of cardiovascular risks. A healthy and balanced gut microbiota not only helps in ensuring proper digestive function and production of vitamins (B and K) but also plays a key role in the immune system of the host.

Environmental factors such as diet, exercise, and early life exposures can significantly impact the composition and activity of the gut microbes. Disturbances in the host-microbe relationship lead to increased metabolic complications like through several different mechanisms. Cardiovascular thrombotic events, such as myocardial infarction and stroke, are a leading…